How does CBD work in the body?

How does CBD work in the body?

A non-intoxicating substance obtained from the cannabis plant is cannabidiol (CBD). Due to its potential therapeutic advantages for various medical ailments, such as anxiety, pain, and inflammation, it has grown in popularity recently. But precisely how does CBD function in our bodies?

The Endocannabinoid system (ECS) in our bodies and CBD interact . The complex network of cell receptors and neurotransmitters known as the extracellular signaling system (ECS) is essential for controlling a number of biological processes, including appetite, sleep, mood, and immunological response .

The ECS mostly contains CB1 and CB2 cell receptor subtypes. Whereas CB2 receptors are prevalent in immune cells and peripheral organs, CB1 receptors are largely concentrated in the brain and central nervous system .

When we eat CBD , it has various effects on the CB1 and CB2 receptors. Tetrahydrocannabinol (THC), the psychoactive component of cannabis, binds to these receptors directly; CBD, however, affects the activation of these receptors by a variety of methods .

Anandamide, a neurotransmitter that interacts with CB1 receptors, is known to be inhibited by CBD. This causes anandamide levels in the brain to rise, which may improve mood, pain perception, and hunger .

Serotonin receptors, which are important in controlling mood, anxiety, and stress, are likewise affected by CBD. Involving these receptors, CBD may lessen anxiety and elevate mood .

The anti-inflammatory and antioxidant properties of CBD have also been demonstrated, in addition to its effects on the ECS .These characteristics may contribute to the explanation of why CBD has shown promise as a potential treatment for ailments like multiple sclerosis, arthritis, and chronic pain .

It is significant to emphasize that further research is required to completely understand the precise processes by which CBD acts in our bodies and to unlock its full therapeutic potential. Nonetheless, the available data indicates that CBD may offer a variety of health and wellbeing advantages, and it is a potential area for further study and development .

The Vanilloid receptor (TRPV1), which is involved in pain perception, and the orphan receptor GPR55, which is present in the brain and may be involved in controlling mood, are two other receptors that CBD may interact with in the body .

The Biphasic nature of CBD’s interaction with the ECS is an intriguing feature. This implies that CBD may have varying effects depending on the amount. For instance, CBD may have an invigorating impact at low dosages while being more sedative at higher ones .

How CBD is ingested can also affect how it functions in the body. CBD must first transit through the digestive tract and liver when taken orally, which can affect its strength and onset time. Nevertheless, CBD can more quickly and directly enter the bloodstream when breathed, hastening the beginning of effects .

While CBD is generally regarded as safe and non-intoxicating, it can interact with some drugs, such as blood thinners, and may induce adverse effects such as diarrhea, exhaustion, and changes in appetite or weight .

The ECS and other receptors interact with CBD to create a variety of potential therapeutic effects, even though the precise processes by which it functions in human bodies are still not entirely understood. We may have a greater knowledge of CBD’s full potential and how it can enhance our health and wellbeing as research advances.

Moreover, studies have demonstrated that CBD can influence the immune system. In one study, it was discovered that CBD decreased the amount of pro-inflammatory cytokines produced as a result of a bacterial infection. This shows that CBD might be useful in treating autoimmune conditions and other conditions .

CBD might have neuroprotective qualities, which means it might aid in defending the brain from harm and deterioration. CBD has been demonstrated in animal experiments to lessen stroke-related damage and enhance cognitive performance in mice with Alzheimer’s disease .

The possible anti-cancer properties of CBD are a different subject of study. According to some research, CBD can stop cancer cells from multiplying and spreading both in test tubes and animal models. To assess whether these results apply to people, more study is required .

It is crucial to remember that while CBD exhibits promise as a potential treatment for a number of health issues, it is not a panacea and should not be used in place of standard medical care. If you are considering using CBD for a health condition, it is important to talk to your doctor first to ensure it is safe and appropriate for your individual needs .


Research has demonstrated that CBD interacts with the Endocannabinoid system and other receptors to produce a variety of potential therapeutic benefits , even if the precise processes by which it functions in our bodies are still not completely understood. We may have a greater knowledge of CBD’s full potential and how it can be used to enhance our health and wellbeing as research on it advances .